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Now, let's talk about the second main characteristic of inflammation in sepsis: **vasodilation and increased vascular permeability**. Imagine the blood vessels in your body as a network of roads that deliver supplies and remove waste. In sepsis, these roads become widened (vasodilation), and the walls of the roads become leaky (increased vascular permeability). The inflammatory mediators we mentioned earlier, like cytokines, cause the blood vessels to relax and dilate, increasing blood flow to the affected areas. This is a normal part of the inflammatory process, designed to bring immune cells to the site of infection. However, in sepsis, this vasodilation becomes systemic (affecting the whole body), leading to a dangerous drop in blood pressure. This is a common and dangerous symptom known as septic shock.
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**Apakah mereka sering mendapatkan kritik?**
